Located on the northeast corner of Scioto and Union Streets, this square brick structure was built in sections from the 1840s through the early 1850s by Dr. Edward Clarke, a dentist originally from Connecticut.
Edward’s son, Dr. Hartley Clarke, also a dentist, raised his family here and left the house to his daughter, Miss Abbe, an accomplished musician. She shared the home with her dear friend, Alice Ada May, for many years before her death.
After Miss May’s death, the house was bequeathed in 1966 to the Pickaway County Historical Society to be used as a museum. A large two-story frame addition was constructed by the Society on the north side of the building to house a meeting room and display area. The museum was dedicated June 18, 1972.
Many items belonging to the Clarke family and to Miss, as well as to other past citizens of Circleville, are now displayed throughout the home. One upstairs room has been furnished as an early dentist’s office as a tribute to the Drs. Clarke and contains the dental cabinet used by Dr. Hartley Clarke.